Advisory Board and Editors Cell Biology
Jeroen Roelofs
Jeroen Roelofs received his Ph.D. (Cum Laude) from the University of Groningen, where he studied cGMP signalling and chemotaxis of Dictyostelium Discoideum. During his postdoctoral work in the Lab of Dan Finley at Harvard Medical School he studied the ubiquitin-proteasome system and discovered a role of several molecular chaperones in the assembly of the proteasome in S.Cerevisiae and human tissue culture cells. Since 2009 he runs his own lab at Kansas State University, where his lab studies proteasome assembly and regulation at the molecular and cellular level in yeast and mammalian tissue culture systems. Recent interests include quality control of assembly and the degradation of proteasomes through autophagy.
Cheryl S Rosenfeld
Prof. Cheryl S. Rosenfeld is a Professor of Biomedical Sciences at the University of Missouri Columbia. Prof. Rosenfeld specializes in studying the effects of maternal diet on offspring, exploring how the in-utero environment can shape risks for later disease. Her research with mice has yielded major breakthroughs. She has determined that an energy-rich maternal diet will result in more male mouse pups, while a restricted-calorie diet produces daughters more frequently. She also established a relationship between a certain hair-coat color and obesity and diabetes in mice. Most recently, the Rosenfeld lab has identified spatial learning disabilities in male deer mice whose mothers consumed a diet supplemented with bisphenol A, (BPA), a known endocrine disruptor and a common pollutant. This disability is expected to hinder the males in navigating to find mates; the finding has implications for deer mice populations exposed to BPA in the wild.
Daniela Rossi
1995: Degree in Pharmaceutical Chemistry, University of Milan
1997: Degree in Pharmacology, University of Milan
2001: Ph.D. in Natural Sciences, University of Zürich
1999-2002: Research fellow at the Imperial College - School of Medicine at St. Mary’s, London
2002-2009: Senior scientist at the University of Milan
Since 2009: Head of the Laboratory for Research on Neurodegenerative Disorders, Fondazione
Salvatore Maugeri – Clinica del Lavoro e della Riabilitazione - IRCCS, Pavia
Michael G. Rossmann
The Hanley Distinguished Professor of Biological Sciences, Purdue Univ; Member of the Nat. Academy of Sciences; Foreign Member of the Royal Society of London; Fellow of the American Association for the Advancement of Science; Past Member of the National Science Board. Awards include the Paul Ehrlich & Ludwig Darmstaedter Prize; the Fankuchen Award; the Louisa Gross Horwitz Prize; the Gregori Aminoff Prize; the Stein and Moore Award; the Ewald Prize; the Elisabeth Roberts Cole Award.
Ligia Rusu
Dr. Ligia Rusu is a Professor within the Department of Kinetotherapy and Sport Medicine at the University of Craiova, Romania.
HIs research areas include neurologic rehabilitation, neuromuscular assessment, physiology and biomechanics. More specifically, sports medicine, neurologic rehabilitation, orthopedic rehabilitation, and orthotics and prosthetics.
Albert Salas-Huetos
Dr. Salas-Huetos obtained his Bachelor of Science (Biology) from the Universitat de Girona (UdG) in 2009, his MSc in Cell Biology in 2010 at the Universitat Autònoma de Barcelona (UAB), and his Ph.D. in Cell Biology (Cum-Laude and Extraordinary Doctorate Award) in 2016 at the same University (UAB). He joined the Genetics of Male Fertility group (UAB) as a PhD Student, and Human Nutrition Unit (Universitat Rovira i Virgili; URV) in 2016 as a Post-doctoral Fellowship. He spent a three-month Post-doctoral stay (September-December 2017) at Universidad de Guadalajara in Mexico. In 2018, he joined the University of Utah (USA) and in 2020 the Harvard T.H. Chan School of Public Health (Harvard University; USA) as a Post-doctoral Fellow. Nowadays he is a Visiting Scholar at Harvard University for the Department of Nutrition, Harvard T.H. Chan School of Public Health and a Post-doctoral Fellow at Universitat de Girona (JdlCI). Currently, he is working on different large international multicentric projects related to genetics and epigenetics of male (in)fertility, and nutrition. The main contributions of his scientific activity are reflected in a total of 63 original articles (Q1: 51/63; first or corresponding author: 23/63) in SCI/JCR-journals (+ 5 submitted), and 3 book chapter (+2 submitted). He has attended 9 national/international conferences as invited (plenary) speaker and he was the leading author of 10 contributions in international conferences (+15 as a collaborator author).
Darren N Saunders
Senior Lecturer in Medicine at the University of NSW and visiting fellow at the Kinghorn Cancer Centre, Garvan Institute in Sydney, Australia. Science communicator and past deputy chair of the Australian Academy of Science Early-Mid Career Researcher Forum. Australian Leadership Award (2012), NSW Life Scientist Research Award (2010).
My research is focused on proteostasis and metabolic reprogramming in cancer and neurodegeneration, integrating various platforms (including proteomics, genomics, and metabolomics) to better understand genotype-phenotype relationships. I have a long-standing interest in protein homeostasis (proteostasis), publishing numerous manuscripts providing mechanistic insights into serpin biology and the Ubiquitin-proteasome system, with more recent work aimed at characterising novel mutations involved in protein misfolding and Ub systems in various disease states. I developed a novel platform for screening protein-protein interactions in situ, and novel proteomics approaches to systematically identify E3 Ub ligase substrates and for exploring interactome diversity in cell signalling. We use a number of models systems including patient-derived iPS cells, patient derived tumour xenografts and transgenic models of cancer and neurodegeneration. I am also collaborating to develop creative technology-based approaches to visualizing and communicating complex data, using music to explore the intersection between genetics and environment.
Primo Schär
PhD University of Berne, Switzerland with Prof. J. Kohli; Research focus: Yeast genetics, mechanisms of meiotic recombination.
Postdoctoral fellow at the University of Berne, Switzerland with Prof. J. Kohli; Research focus: Yeast genetics and DNA Mismatch Repair in Meiotic Recombination.
Postdoctoral fellow at the Imperial Cancer Research Fund (Cancer Research UK), London UK, with Prof. Tomas Lindahl; Research focus: Function of DNA ligases in yeast and mammalian DNA repair, DNA base excision repair.
Junior research group leader at the Institute of Molecular Cancer Research, University of Zürich, Switzerland; Research focus: Genome Stability, DNA double strand-break repair and DNA base excision repair in yeast and mammalian cells.
Since 2003 Professor and research group leader at the Department of Biomedicine, University of Basel, Switzerland; Research focus: Molecular mechanisms underlying (Epi)Genome plasticity in stem cells, DNA base excision repair in DNA demethylation and cell fate programming.
Eric C Schirmer
Eric Schirmer received his PhD from the University of Chicago where he studied the HSP100 family of chaperones and their interactions with prions. His post-doctoral research at the Scripps Research Institute focused on assembly of the nuclear lamina and proteomics of nuclear envelope transmembrane proteins. Since establishing his laboratory at the University of Edinburgh he has been investigating tissue-specific differences in the nuclear envelope proteome and the functions of these proteins in tissue-specific patterns of spatial genome and cytoskeletal organization, along with studies of lamin structure, nuclear size regulation and herpesvirus egress through the nuclear membranes.
Mirela Sedic
Dr Mirela Sedic (born Bauman) is Principal Scientist at the Institute for Anthropological Research Zagreb. She has authored over 50 scientific publications in peer-reviewed journals including high-impact journals such as BBA Molecular Basis of Disease, Molecular Cancer, The Journal of Pathology, Molecular Cancer Therapeutics, Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry and Cancer Treatment Reviews.
She was the co-PI of international collaborative project with Functional Genomics Center Zurich in Switzerland (PRIME-XS-0000184 Proteomic profiling of retinal proteins from rat model of age-related macular degeneration 2012-2014) and the PI of the University of Rijeka grant “Screening and biological evaluation of acid ceramidase and sphingosine kinase inhibitors as a new class of anti-tumour agents” (2014 – 2017). She is currently the PI of the project funded by the Croatian Science Foundation “Dissecting the mechanisms of therapy resistance in BRAF-mutant colon cancer using an integrated –omics approach” (2019 – 2023) and the PI of the University of Rijeka research grant “Molecular features associated with BRAFV600E-mutated versus wild type BRAF colorectal cancer” (2019-2022). She is also the PI of the project No. 3238 - EPIC-XS 012: “Proteomic analysis of acquired resistance to vemurafenib in BRAF V600E–mutant colon cancer cells” (2019 - 2022) in collaboration with the Functional Genomics Center Zurich in Switzerland.
Violaine Sée
Violaine See completed her doctorate on progammed cell death signaling at the University of Strasbourg (France). After a post-doctoral position in Liverpool on NF-kappaB dynamics she obtained a Fellowship to work on intracellular signalling dynamics at the University of Liverpool. She now leads a research group focusing on cellular adaptation to low oxygen levels and the dynamics of hypoxia inducible factor using single cell imaging and advanced fluorescence microscopy